Crystal structure of 3-(2-chloro-benzyl)-7-[4-(2-chloro-benzyl)-piperazin-1-yl]-5,6,8-trifluoro-3H-quinazolin-4-one, C 26 H 21 Cl 2 F 3 N 4 O
نویسندگان
چکیده
Abstract C 26 H 21 Cl 2 F 3 N 4 O, monoclinic, Pc (no. 7), a = 21.218(6) Å, b 5.9599(16) c 9.439(3) β 99.295(3)°, V 1177.9(5) Å , Z 2, R gt ( ) 0.0471, w ref 0.1282, T 296(2) K.
منابع مشابه
N-Benzyl-2-(3-chloro-4-hydroxyphenyl)acetamide
The title compound, C(15)H(14)ClNO(2), was synthesized as part of a project to generate a combinatorial library based on the fungal natural product 2-(3-chloro-4-hy-droxy-phen-yl)acetamide. It crystallizes as non-planar discrete mol-ecules [the peripheral 3-chloro-4-hy-droxy-phenyl and benzyl groups are twisted out of the plane of the central acetamide group, with N-C-C-C and C-C-C-C torsion an...
متن کامل3-Chloro-6-[4-(2-pyridyl)piperazin-1-yl]pyridazine
In the title compound, C(13)H(14)ClN(5), the piperazine ring adopts a chair conformation and the dihedral angle between the aromatic rings is 13.91 (7)°. The crystal structure is stabilized by weak inter-molecular C-H⋯N hydrogen-bond inter-actions.
متن کامل3-[(2-Chloro-6-methylquinolin-3-yl)methyl]quinazolin-4(3H)-one
In the title mol-ecule, C(19)H(14)ClN(3)O, the quinoline and quinazoline ring systems form a dihedral angle of 80.75 (4)°. In the crystal, the mol-ecules are linked by pairs of C-H⋯N hydrogen bonds into centrosymmetric dimers, generating R(2) (2)(6) ring motifs. The structure is further stabilized by C-H⋯π inter-actions and π-π stacking inter-actions [centroid-centroid distances = 3.7869 (8) an...
متن کاملBenzyl N-(3-chloro-4-fluorophenyl)carbamate
The title compound, C(14)H(11)ClFNO(2), the phenyl ring (A), the chloro-fluoro-phenyl ring (B) and the central ketone O/C/O group (C) are not coplanar, with dihedral angles B/C = 31.6 (2), A/B = 21.3 (2) and A/C = 50.1 (2)°. The crystal packing is stabilized by N-H⋯O and C-H⋯O inter-actions.
متن کاملN-Benzyl-2-(2-chloro-4-methylphenoxy)acetamide
The structure determination of the title compound, C(16)H(16)ClNO(2), was performed as part of a project on the inter-actions between small organic mol-ecules and proteins. In the crystal structure, the dihedral angle between the two aromatic rings is 16.14 (12)°. The molecules are connected via N-H⋯O hydrogen bonding into chains, which extend in the direction of the b axis.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Zeitschrift Fur Kristallographie-new Crystal Structures
سال: 2021
ISSN: ['2197-4578', '1433-7266']
DOI: https://doi.org/10.1515/ncrs-2021-0085